Abstract
IV-PCA can control postoperative pain effectively because opioid concentrations in the blood can be increased quickly. Control of postoperative pain with IV-PCA is prompt. IV-PCA has been widely used to treat postoperative pain. Patients' satisfaction with IV-PCA is high. Recent increasing demand of prophylactic postoperative anticoagulation has further increased the role of IV-PCA in postoperative pain control. Proper settings of IV-PCA are mandatory for a safe method of postoperative pain control. However, the side effects of opioids hinder effective postoperative pain control with IV-PCA. Some side effects can lead to severe complications. Early recognition, treatment, and prevention of side effects of opioids are important. We describe the side effects of opioids used for IV-PCA and their treatments.