Abstract
Re-intubation may occasionally be required after neuromuscular blockade reversal by sugammadex. Four adult patients received rocuronium 0.6-1.4 mg/kg at 19, 210, 270 and 360 min after sugammadex administration. For repeat dose timepoints >210 min, onset times of rocuronium were within 2 minutes, except for one patient who received rocuronium 19 min after sugammadex. The duration times of the block in four patients were more than 30 min after repeat dose of rocuronium. It was demonstrated that rapid re-onset of blockade occurred after repeat dose of 0.6-1.4 mg/kg of rocuronium as early as 19 min after sugammadex in re-surgical adult patients.
