Abstract
When providing postoperative analgesia for patients receiving antithrombotic therapy, we should have thorough knowledges of the type and doses of antithrombotic medications, and the diseases they are prescribed for. After taking all kinds of risks the patient may suffer into consideration, we should determine how we deal with antithrombotic therapy during the perioperative period. Upper abdominal surgery is frequently associated with severe postoperative pain. Thus, postoperative pain management should be facilitated via a context-sensitive approach. This approach tries to optimize postoperative analgesia by timely utilization of all kinds of analgesic tools after considering the pathophysiological and biochemical contexts regarding the type of surgery, rehabilitation protocols and pain. As the regional anesthesia technique can provide effective analgesia without affecting the physiological functions of the patient, it can play a major role in context-sensitive analgesia for patients receiving antithrombotic therapy.