Abstract
We experienced general anesthesia management during resection of ovarian tumor in two cases with anti-NMDA receptor encephalitis. Case 1 showed significant psychological symptoms, making it difficult to determine the timing of surgery. Case 2 was artificially ventilated before the surgery, because of the development of central respiratory disturbance. Both surgeries were uneventfully performed, and the patients were discharged from the hospital. For this disease, resection of tumor is recommended as a therapeutic treatment, indicating an increase in the number of cases for anesthetists in the future. Although problems in anesthesia management and frequency of complications have yet to be reported in patients with this disease, further analysis on accumulated case data is warranted.