Brugada Syndrome and QT Prolongation Syndrome

Abstract

  Brugada syndrome is defined as electrocardiographic (ECG) changes consisting of ST elevation in V1-V3 lead and is induced by ventricular fibrillation. This hereditary syndrome is often the cause of death in younger adult men, predominantly. Implantation of ICD is a definite therapy to prevent sudden death.
  QT prolongation syndrome (LQTS) is defined as prolonged QT interval (QTc > 440msec) and causes malignant ventricular arrhythmias to the development of torsade de pointes. This syndrome is heredity or induced by several drugs. The first therapy for LQTS is intravenous adopted be-ta blockers, mexiletine and verapamil. However, patients who have had mortal arrhythmias, including VF, are indicated for ICD implantation.
  Anesthetic consideration of the patients with implanted ICD is to arrest the ICD function and attach the DC pads on the thorax during the operation.