Abstract
The information derived from the isobologram, which shows the relationship between hypnotics and analgesics, including MAC reference lines, may be useful, because the current role of electroencephalogram-related monitors to prevent intra-operative awareness depends on the anesthetics used. The SmartPilot View, developed by Dräger Medical, simulates effect site concentrations of opioids, intravenous and volatile anesthetics. The status of anesthetic levels as a result of a combination of hypnosis and analgesia is expressed as a closed circle (isobole) on the isobologram. An isobole always shows both the current anesthetic status and the status 15 minutes in the future. The SmartPilot View is expected to contribute to the maintainance of adequate anesthesia levels as well as the prevention of intra-operative awareness, because anesthesiologists can obtain the current anesthesia status correctly and also intuitively.