Abstract
We assessed the incidence of residual neuromuscular block (train of four ratio<0.9) after reversal with neostigmine or sugammadex following administration of rocuronium without using neuromuscular monitor. After reversal of neuromuscular block, adequate recovery was judged subjectively by the attending anesthesiologist and the trachea was extubated afterward. The incidence of residual paralysis just after extubation was 23.9% with neostigmine but was significantly reduced to 4.3% with sugammadex. Factors of residual paralysis in the neostigmine group were older age, higher dose of rocuronium supplementation, lower dose of neostigmine, and shorter time from the last rocuronium administration to neostigmine administration, but no clear factors of residual paralysis in the sugammadex group were found.
