Abstract
There has been recent tendency to avoid anesthetic premedication, but this increases the risk of an excessive rise in blood pressure due to mental strain especially for patients with hypertension. A retrospective study was conducted to examine blood pressure, heart rate and percutaneous oxygen saturation when entering an operating room to assess the effect of premedication on blood pressure and heart rate during an operation. Patients without complications and those with complications of essential hypertension were identified according to their anesthesia records and divided into 4 groups depending on the use of premedication. Comparative items were specified as follows : blood pressure, double product, heart rate, and percutaneous oxygen saturation. Systolic blood pressure in patients with hypertension who were administered midazolam as premedication was significantly lower on entering the operating room than in patients who did not receive such premedication. On the other hand, percutaneous oxygen saturation was significantly lower than in non-premedicated patients. Premedication with midazolam is effective to control the excessive rise of blood pressure when entering an operation room but requires attention to low percutaneous oxygen saturation.
