Impact of Intraoperative Goal-directed Therapy with a FloTrac^TM/Vigileo^TM Sensor on Perioperative Management

Abstract

We performed goal-directed therapy (GDT) with a FloTrac^TM/Vigileo^TM in order to determine its usefulness. In this study, we examined the impact of perioperative management with GDT on renal function and the length of the intensive care unit (ICU) stay. This study focused on pancreatic surgeries. For Group C (n＝24), intraoperative management was provided by measuring mean blood pressure, heart rate, and urine volume as parameters. For Group GDT (n＝23), stroke volume variation and stroke volume index, obtained from the FloTrac^TM/Vigileo^TM sensor, were also used as parameters. The primary endpoints were pre- and postoperative blood urea nitrogen (BUN), creatinine, and length of ICU stay. The length of ICU stay in Group GDT (1.3±0.6 days) was significantly shorter than in the Group C (2.5±2.2 days) (P＝0.043). There were no significant differences in pre- and postoperative BUN or creatinine levels.