Intraoperative Glycemic Control

Abstract

Intraoperative glycemic control is definitely important, because perioperative hyperglycemia is considered to be an independent risk factor for morbidity and mortality associated with surgery. During anesthetic management, energy demand/supply balance should be appropriately maintained and possible adverse events exaggerated by hyperglycemia should be prevented. Several factors, such as surgical stress and anesthetics, significantly modify intraoperative glucose metabolism. Unfortunately, mechanisms underlying the modifying effects of these factors on intraoperative glucose metabolism have not been elucidated so a standard regimen for intraoperative glycemic management has not been established. Further investigations focusing on intraoperative glucose metabolism are definitely required in order to establish management guidelines which can contribute to improving surgical prognosis.