Pitfalls in Translational Research

Abstract

Translational research aims to develop a new therapeutic strategy based on findings from basic science. Scientists, clinicians and patients keen for new treatment options are disappointed to see many projects end in failure. Even though clinicians are not usually required to know about the basic science during their daily practice, it is worth knowing why many projects seeking a new therapy are unsuccessful.

In the present paper, we discuss how we can evaluate data from basic science in terms of reproducibility and consistency with clinical medicine.