2017 Volume 37 Issue 3 Pages 355-360
The role of nonopioid analgesics in the pharmacotherapy of cancer pain is important. The use of nonopioid analgesics may allow the side effect reduction of opioids. Nonopioid analgesics are classified roughly into non-steroidal anti-inflammatory drugs（NSAIDs）and acetaminophen. From their mechanism of action, NSAIDs pose the risk of gastrointestinal disturbance, renal dysfunction, and platelet disorder. In recent years a cardiovascular risk has been found as well. Whereas acetaminophen requires attention about liver dysfunction. We give an outline around the point where you should be careful about nonopioid choice.
