Circulatory Control via Neural Stimulation：Merits and Demerits

Abstract

Among many regulatory systems that maintain arterial blood pressure, the arterial baroreflex system plays a dominant role in arterial pressure regulation responding within seconds to minutes after disturbances. We have quantified characteristics of the arterial baroreflex-mediated sympathetic arterial pressure regulation using white noise analysis, a method used in the engineering field. Experimental results indicate that neural regulation is much faster and stronger than humoral regulation, so circulatory control via neural stimulation should contribute to the management of circulation including the perioperative period. Nevertheless, difficulty in noninvasively constructing neural interface limits the application of neural stimulation for circulatory control. Further research is required to develop an easy and effective methodology for neural stimulation.