Type I Kounis Syndrome Induced by Sugammadex Administration：A Case Report

Abstract

A 66-year-old male patient, with a history of allergy to pineapple and house-dust, underwent endovascular surgery under general anesthesia and was administered sugammadex（200 mg）at the end of surgery. A few minutes later, generalized rash and decrease in blood pressure were observed. Because a hypersensitivity reaction to sugammadex was suspected, 0.2-mg adrenaline and 500-mg methylpredonisolone were administered to improve the patient’s condition. An electrocardiogram revealed ST elevation in the inferior leads, which improved spontaneously after blood pressure improved. Coronary angiography revealed no occlusion of the coronary artery. A skin-prick test, performed two months later, revealed negative results for sugammadex.