Perioperative Use of Colloids

Abstract

Fluid optimization is one of the most important keywords in perioperative settings, and goal-directed fluid therapy（GDFT）is implemented as a promising strategy for perioperative fluid therapy. GDFT consist of baseline crystalloid infusion and fluid challenge with colloid. Voluven is the most frequently used synthetic colloid in Japan. A relatively high administrable upper limit of 50 mL/kg/day allows clinicians to avoid the use of albumin products which had been in large amounts until recent years. In terms of influence on kidney function and blood coagulation, which is known to be a disadvantage of HES（hydroxyethyl starch）products, recent reports show that voluven is comparable to crystalloids in perioperative settings, though more studies are needed. Finally, a questionnaire survey on intraoperative fluid usage was conducted and some results are introduced.