Abstract
The many serum parameters were measured to examine the sympathetic nervous system after hemorrhagic shock in rabbits. The plasma epinephrine faster responded to blood loss. It increased one hundred times from control state, when blood loss reached to 15mg/kg body weight.
On the other hand, norepinephrine began to decrease at 15∼20ml/kg of blood loss and drastically increase again in blood loss over 25mg/kg. The plasma concentration of lactic acid, glucose, osmolality and potassium were elevated, and pH and sodium decreased over 20ml/kg of blood loss. The 20ml/kg of hemorrhage without infusion led to the "sick cell". The blood loss beyond 35ml/kg was lethal in rabbits and almost all parameters were abnormal.
In summary, according to the change of plasma norepinephrine, sympathetic nervous system may be depressed at relatively early stage during hemorrhagic shock.
