Abstract
Kabuki make-up syndrome is a rare congenital malformation syndrome. The patient has several abnormalities which include the peculiar-looking face similar to Japanese Kabuki player, skeletal anomalies, dermatoglyphic abnormalities, mild to moderate mental retardation, and postnatal growth retardation. The problems regarding anes-thetic management are difficulties in tracheal intubation, epidural catheter placement, and vulnerability to bacterial infection. We experienced five anesthetic managements in two patients with this syndrome. In the first case, intra-and post-operative hypo-xemia developed, due possibly to pleuritis attributable to immuno-deficiency and impaired pulmonary function. In the second case, anesthetic courses were uneventful.
