Abstract
We investigated stress responses during gynecological laparoscopic surgery. After informed consent, 10 adult female patients, ASA physical status I-II, were randomly divided into two groups of 5 each: an abdominal wall lift (L) group and a CO2 insufflation (G) group. Blood was sampled 7 times, and blood sugar, dopamine, adrenaline, noradrenaline, adrenocorticotropic hormone (ACTH), cortisol, and antidiuretic hormone (ADH) were measured.
Noradrenaline during pnermoperitoneum, ADH 60 min after insufflation, dopamine right after desufflation and blood sugar level at the end of surgery were significantly increased in the G group compared with the L group. In both groups, ACTH and cortisol were signifi-cantly increased during laparoscopic surgery, with no significant difference between the two groups. No significant changes in catecholamines in the L group were observed.
From these results, we conclude that the abdominal wall lift method is physiologically superior to the CO2 insufflation method.