Abstract
During anesthesia, the state of oxidation reduction (redox state) in the liver may be influenced by many factors such as preoperative starvation, liver blood flow and metabolic malfunction resulting in surgical diabetes.
It is well known that redox state and arterial ketone body ratio (AKBR) correlate to each other. However, acetone, which is one of the ketone bodies, has not been taken into account in previous research due to the difficulty in measuring patients' expired gas.
Therefore, we established a method for detecting acetone in expired gas and found a negative correlation between acetone in expired gas and AKBR.
Finally, we conclude that real-time liver function can be noninvasively assessed during anesthesia by measuring acetone in expired gas.
