Abstract
We evaluated changes in intra-ocular pressure (IOP) and cerebral hemoglobin oxygen saturation (rSO2) during laparoscopic surgery in the Trendelenburg position(n=16) Continuous lumbar epidural block with 1.5% mepivacain was performed on all patients. These patients were allocated randomly to two groups: continuous propofol infusion group (group Epi+Propofol) and isoflurane, oxygen and nitrous-oxide group (group Epi+GOT). In group Epi+GOI, the IOP elevated significantly 30min after the intra-abdominal CO2 insufflation and Trendelenburg positioning. However, in group Epi+Propofol, the IOP did not show any change throughout the study, and was significantly lower than that in group Epi+GOI. The rSO2 in both groups did not change throughout the study, and no significant differences were observed between two groups. Therefore, propofol did not increase IOP during laparoscopic surgery in the Trendelenburg position.
