Abstract
Abnormal movements, posturing and frank seizure activity have been widely reported in association with propof of anesthesia.
We report one case of seizure at the end of propofol anesthesia.
A 24-year-old woman (weight 50kg) underwent thyroidectomy for Basedow's disease. She had no history of epilepsy. She received fentanyl 200μg, propofol 80mg and vecuronium 8mg for induction of anesthesia. Anesthesia was maintained with propofol (total 1, 010mg), nitrous oxide 50% in oxygen and fentanyl (total 500μg). At the end of surgery, nitrous oxide and propof of were discontinued. Atropine sulfate and neostigmine were administered intravenously to reverse neuromuscular blockade. As she opened her eyes and could maintain adequate spontaneous ventilation, the tracheal tube was extubated. After a few minutes, she developed tonic-clonic seizures for about one minute. Seizure recurred three times over the course of ten minutes. The seizures stopped without treatment. An electroen-cephalograph performed after surgery was normal.
