Abstract
To prevent hypertension following coronary artery bypass surgery, we administered morphine after cardiopulmonary bypass.
29 patients undergoing coronary artery bypass surgery received high dose fentanyl anesthesia. In 19 patients of these, group FM, 0.3-1.7mg/kg morphine was administered after cardiopulmonary bypass, while in 10 patients group F, morpine was not administered. Between these two groups, we compared maximum values of heart rate, systolic and diastolic blood pressure, and rate pressure product(RPP)in the perioperative period.
In the first postoperative period (0-6 hours after operation), patients in group FM had lower systolic blood pressure (P<0.01), and lower RPP(P<0.05) than those in group F, both statistically significant.
Morphine, administered after cardiopulmonary bypass, is effective in preventing hypertension in the early post-operative period of coronary artery bypass surgery.
