Abstract
The 9 cases of Malignant Hyperthermia (MH) were observed during the 5 year period from 1982 to 1987 in our institutions. Of these 9 cases, neuroleptics had been administered for shizophrenia in 2 cases. Cautious management of anesthesia is necessary when the patient has been treated with neouroleptics. In 2 cases, MH became apparent after anesthetic procedure. It must be noted that diagnosis of MH is assumed not only in peri -operative but also in post-operative period. Misunderstanding that muscle rigidity was caused by shortage of succinylcholine (SCC), additional administration of SCC was performed in 3 cases. Consequently, administration of SCC should be done cautiously. Tachycardia was observed most frequently (6 cases) in circulatory abnormalities. There is possibility that tachycardia may be recognized to be caused by shortage of anesthetics. Supplementary administration of anesthetics must be avoided in such cases. Dantrolene therapy was terminated according to decline of serum creatine phosphokinase values. As a result of dantrolene therapy in this manner, there was no case who relapsed into MH.
