Abstract
Objective : To improve endometrial cytology accuracy, we evaluated the usefulness of architectural atypia as a possible diagnostic criterion. Our criterion was not satisfactory in consistency and reproducibility. We examined the utility of new criteria combined with cell clumps.
Study Design : We selected 144 cytologically suspicious cases for which histological diagnoses were available, dividing them into 2 groups-106 in group A with criteria for a decision that cell clusters were classified into nine types, and 38 in group B with new criteria for a decision that cell clusters were classified in four types.
Results : Histological findings for Group A showed 40 (37.7%) that were benign, 65 (61.3%) that were endometrial hyperplasia, and 1 (1.0%) that was endometrial adenocarcinoma, grade 1. In group B, 12 (31.6%) cases were benign, 25 (65.8%) were endometrial hyperplasia, and 1 (2.6%) was endometrial adenocarcinoma, grade 1. No significant difference was observed between groups.
Conclusions : New criteria combined with cell clumps were comparable in diagnostic accuracy for endometrial hyperplasia.
