Neuroendocrine carcinoma of the uterine corpus—A case report—

Abstract

Background : We report a rare case of neuroendocrine carcinoma arising in the endometrium.
Case : A 66-year-old woman with abdominal pain was found in magnetic resonance imaging (MRI) to have a huge mass in the abdominal and pelvic cavity. Endocervical smears showed round tumor cells isolated or in weakly bound clusters. Immunocytochemically, tumor cells were positive for synaptophysin. Histologically, the tumor shows solid growth with necrosis and a high mitotic rate.
Conclusion : Few reports have been made on neuroendocrine tumor differentiation in primary endometrial cancer, and, more examination is needed.