Abstract
Background : Plasma cell neoplasm is clinically recognizable as a bone and soft-part tumor. We report a case of anaplastic plasmacytoma involving the chest wall in which imprint cytology specimen observation was useful in suggesting its plasmacytic origin.
Case : An 82-year-old man was found in chest computed tomography (CT) to have a left anterior chest mass 10 cm in diameter involving the ribs. The surgically resected tumor, consisting of large atypical cells with eccentric oval nuclei and prominent nucleoli arranged in a medullary growth pattern together with bizarre multinucleated tumor cells, was considered histologically to be anaplastic plasmacytoma. Differential diagnoses included malignant epithelioid neoplasms such as metastatic carcinoma, epithelioid sarcoma, and hematological neoplasm.
Conclusion : Imprint cytology is useful in definitively diagnosing plasma cell neoplasm, including the anaplastic variant.
