A case of extraskeletal myxoid chondrosarcoma cellular variant diagnosed by squash preparation cytology

Abstract

Background : We report a case of extraskeletal myxoid chondrosarcoma cellular variant (ESMCSCV) preoperatively diagnosed by squash preparation cytology.
Case : A 69-year-old man had a left thigh mass difficult to diagnose histologically due to high cellularity and minimal myxoid stroma. A characteristic, well-differentiated structure was absent. Squash preparation cytology, however, identified a coffee-bean-like nuclear groove and myxoid-hyalizing stroma and a cord-like pattern.
Conclusions : Cytological features effectively identify ESMCSCV, especially in the minute material from preoperative needle specimens.