Abstract
Objective : Pituitary-tumor imprint cytology was conducted to determine whether cytological diagnosis was possible and whether three types—GH-PRL-TSH, ACTH, and FSH-LH/null cell—could be differentiated.
Study Design : Touch preparations for 94 pituitary adenoma cases were prepared using surgically resected specimens for frozen sections. Cytological specimens were then compared to histological specimens.
Results : Cytological diagnosis was possible in 86 cases (91.5%). Histological subclassification fell roughly into three imprint cytology types—GH-PRL-TSH, ACTH, and FSH-LH/null cell. Observing cell shape, cohesiveness, nuclear location, and fibrous bodies and secretory granules is thus important for cytologically classifying pituitary adenoma.
Conclusions : Pituitary-adenoma in touch preparation has proved useful supplementing both intraoperative consultation and pathological diagnosis.
