2012 Volume 51 Issue 2 Pages 132-136
Background : Primary vaginal lymphoma is very rare. We report cytological findings for a vaginal stump and urine in a case of vaginal large B cell lymphoma (DLBCL).
Case : A 76-year-old woman admitted for vaginal bleeding had a 48×51×53 mm mass at the vaginal stump found in cytological examination to have large round solitary cells with scant cytoplasm. Cytological urine examination also showed loosely aggregated cells with scant cytoplasm, round or irregular nuclei with conspicuous nucleoli, and a coarse granular chromatin pattern. Immunohistochemical staining of a vaginal tumor biopsy specimen indicated DLBCL.
Conclusion : Primary vaginal DLBCL should be suspected when cytological tumor examination shows isolated lymphoid cells with scant cytoplasm or groups of loosely aggregated lymphoid cells with scant cytoplasm.