2012 Volume 51 Issue 2 Pages 147-148
We report a rare case of ascites cytology showing renal cell carcinoma. Malignant cells in ascites have abundant, clear, and vacuolated cytoplasm, including glycogen and unusual nucleoli. Sudan III staining showed positivity for lipoid granules in cytoplasm. Atypical cell clusters resembled a chrysanthemum flower.
In cell block specimens, immunohistochemical staining showed significant renal cell carcinoma findings. Cell block specimens were useful in differentiating adenocarcinoma in ascites fluid. A Sudan III staining proved simple and useful in helping to determine renal cell carcinoma.