Abstract
Background : We report the cytological and histological findings of breast cancer with cartilaginous and osseous metaplasia.
Case : A woman in her 70s seeking a definitive diagnosis of a 2 cm mass in the left breast underwent AB and ultrasonography. Fine-needle aspiration cytology yielded a diagnosis of carcinoma necessitating surgical resection. The cytological specimens showed many loosely scattered sarcomatoid cells and a few osteoclast-like giant cells. Histologically, carcinomatous, cartilaginous and osseous components occurred together with transitional tissue among the components. Immunohistochemically, the carcinomatous component was positive for EMA and cytokeratin. The cartilaginous and osseous metaplasia components were positive for vimentin. The transitional tissue components were positive for vimentin and cytekeratin.
Conclusions : It was said from the colourfulness of the organization that with many cases that had difficulty in diagnosis by the fine needle aspiration cytology, but, as for the carcinoma with cartilaginous and osseous metaplasia, it was thought that I could give this organization-shaped diagnosis precision by observing it in detail.
