A case of coexisting adenocarcinoma in situ with lobular endocervical glandular hyperplasia and uterine cancer

Abstract

Background : We report herein on a case of coexistence of lobular endocervical glandular hyperplasia (LEGH) and adenocarcinoma in situ (AIS).
Case : A 53-year woman was referred to us for postmenopausal bleeding. Endometrial cytology showed well-differentiated endometrioid adenocarcinoma, and cervical cytology showed yellowish intracytoplasmic mucin associated with LEGH, light yellowish color atypical of LEGH, and hyperchromatin associated with AIS. The LEGH component was positive for HIK1083 whereas the atypical LEGH and AIS were negative. The region of LEGH was separated from the endometrial tumor.
Conclusion : A case of LEGH and AIS was evaluated, and we were able to detect the characteristic findings with preoperative cytology.