Abstract
Background : We report herein on a case of suspected malignant lymphoma based on findings from urine via the patient’s catheter. In addition to the conventional method, our report focuses on the cytological findings from liquid-based cytology (LBC method).
Case : One year previously, a 200 mm tumor was found in the left ureter on MRI in an 85-year-old-male. The tumor was diagnosed as a diffuse large B-cell lymphoma (DLBCL), and chemotherapy was performed. At the present hospital visit, prostate removal surgery was performed, and the diagnosis was confirmed as DLBCL. Malignant lymphoma was suspected based on the first catheter urine. Atypical cells appeared with a large nucleus/cytoplasmic (N/C) ratio, with large bizarre nuclei demonstrating coarse granular chromatin and nucleoli. With the LBC method, cells were easily observed to appear to fall apart. Atypical cells in the LBC specimen tested positive for CD20 and CD79a.
Conclusion : The LBC method is useful if immunostaining is required for most inflammatory cells.
