Abstract
Objective : Solid papillary carcinomas (SPCs) of the breast, the disease unit newly added in the revision of the WHO classification of 2012, are classified as one of the intraductal papillary lesions. We examined the cytological findings of SPCs and compared with those of intraductal papillary carcinomas (IPCs) also an intraductal papillary malignant lesion, and studied whether it would be possible to make a preoperative cytological diagnosis.
Study Design : We examined 6 patients who had been histologically diagnosed as having SPCs for cell imaging of fine-needle aspiration cytology (FNA). We also made a comparative study of the FNA findings of 5 patients who had been diagnosed as having IPCs.
Result : Our findings suggested that the diagnostic clues of SPCs which can distinguish them from IPCs in FNA findings are the presence mucinous substance, fine delicate capillary vessels, discohesive small clusters of cells and numerous single cells, and cuboidal and polygonal cells.
Conclusion : A reliable cytological differential diagnosis of SPCs versus IPCs can be possible through recognizing some characteristic findings of SPCs through FNA findings.
