Abstract
Background : We experienced one case of intraductal papillary mucinous neoplasm (IPMN) with the appearance of signet ring cell-like cells. We examined the characteristic cell findings with touch smear cytology and we report our findings herein.
Case : A 63-year-old woman had a branch type IPMN identified eight years previously and was undergoing follow-up observation. Because increase of the cyst diameter and the expansion of the pancreatic duct were accepted, the patient underwent a pancreatic tail resection. Against the backdrop of inflammation and a small amount of mucus in the diagnosis tumor cell seal, signet ring cell-like cells containing prominent mucus was observed in loose coupling of isolated or sporadic formation. In the histopathological findings, signet ring cell-like cells were observed in the vicinity of the villous growth component. The pathological diagnosis was determined as intraductal papillary mucinous carcinoma, and it was diagnosed as the intestinal type because it was positive for MUC2 staining.
Conclusion : The appearance of signet ring cell-like cells should promote a diagnosis that assumes the intestinal type and gastric type of IPMN. It is possible to identify the subtypes by adding MUC staining.
