2016 Volume 55 Issue 3 Pages 160-164
Background : Chondrosarcomas account for approximately 30% of all malignant bone tumors, and its subtype, clear cell chondrosarcoma (CCCS), accounts for only about 2% of all chondrosarcomas. Therefore, CCCS is an extremely rare malignant tumor. Herein, we report on the cytological findings of a case of CCCS.
Case : A 40-year-old Japanese man visited our hospital with a complaint of worsening right hip joint pain. Image examinations revealed a bone tumor in the right femoral head and neck. The results from a needle biopsy pointed to a suspected diagnosis of CCCS. Extensive resection of the right femoral tumor was carried out.
Conclusions : In the present CCCS case, we recognized epithelioid clear cell clusters resembling a chondroblastoma or metastatic clear cell carcinoma of renal or ovarian origin. In addition, multinucleated osteoclastic giant cells, osteoid-like substances and conventional chondrosarcomatous components were also demonstrated. Based on our findings we suggest that the accuracy of a cytological examination is adequate for the intraoperative diagnosis of CCCS when the significance of each finding is evaluated in intimate correlation with the clinical information and radiological findings.
