A trial for subclassification of koilocytosis on cervical cytology

Abstract

A possible cytological classification of koilocytosis in cervical cytology was proposed by comparison to the results of high-risk group HPV-DNA test. We used cervical cytology slides with koilocytosis obtained from 39 HPV-positive and 12 HPV-negative patients. According to the cytological features, the koilocytes were divided into 2 types (type Ⅰ and type Ⅱ). Type Ⅰ koilocytes showed a clear perinuclear hallow. Type Ⅱ koilocytes showed bizarre nuclei and relatively high N/C ratios. Our results suggest that type Ⅱ koilocytes appear frequently in high-risk HPV-positive cases.