The Journal of the Japanese Society of Clinical Cytology
Online ISSN : 1882-7233
Print ISSN : 0387-1193
ISSN-L : 0387-1193
Brief Notes
A case of cervical cancer with a combination of adenocarcinoma and small cell carcinoma components
Yusuke TAKANEZAWA, Atsushi KATO, Takashi KUSAKABE, Kazuyuki TAKEICHI, Takanori KWAGUCHI
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2017 Volume 56 Issue 1 Pages 39-40

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Abstract

We report the case of a 30-year-old pregnant woman with uterine cervical cancer, in which the tumor contained both small cell carcinoma and tubular adenocarcinoma components. Cytology showed atypical cells with small bare nuclei, scattered singly or in loose clusters, in addition to atypical glandular tissue. Cervical biopsy demonstrated both small cell carcinoma and tubular adenocarcinoma components. On immunohistochemistry, the small cell carcinoma cells showed positive staining for chromogranin A, somatostatin, NSE and SSTR2. At 29 weeks of gestation, the patient underwent abdominal cesarean section, delivering a female baby, followed by radical hysterectomy ; thereafter, she received chemotherapy. Until now, there has been no evidence of recurrence.

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© 2017 The Japanese Society of Clinical Cytology
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