2017 Volume 56 Issue 6 Pages 271-275
Objective : We attempted to improve the cell collection methods during the preparation of urine specimens and performed cytological analysis for high-grade urothelial carcinoma (HGUC) to increase the diagnostic accuracy.
Study Design : The study specimens comprised 491 natural urine samples. We compared the numbers of the collected cells and the detection rates of the atypical cells between the wing-type and conventional-type of centrifuge. Suspicious cases were compared to the histological diagnosis.
Results : The median of the collected cell number and the detection rate of the atypical cells in the wing-type centrifuge were significantly larger than those of the conventional-type (p<0.001). The “Suspicious cases” included six Negative, 53 Atypical cells, 74 Suspicious for malignancy, and two Malignant. Nine out of 15 (60%) Atypical cells, and 24 out of 35 (69%) Suspicious for malignancy were histologically diagnosed as HGUC. The specimens assessed as Suspicious contained small atypical cells.
Conclusion : Usage of the wing-type centrifuge can improve cell collection numbers and atypical cell detection.
