2018 Volume 57 Issue 6 Pages 294-299
Background : Myeloid sarcoma (MS) is an extramedullary tumor composed of immature myeloid cells. Herein, we report a case of myeloid sarcoma in whom the presenting manifestation was a vulval mass.
Case : A female patient in her 30’s presented to our hospital with pain in the right labium minus and clitoral swelling. Physical examination revealed a yellow tumor measuring 2 cm in diameter, extending from the right labium minus to the clitoris. Pelvic MRI revealed an enhanced irregularly shaped mass lesion measuring 3×4×2 cm in size. Hematological examination revealed normal results of a complete blood count (CBC) : WBC count 5600/μl ; Neutro : 65.3%, Lymph : 20.9%, Mono : 8.2%. The results of conventional cervical, endometrial and vulval cytological examinations were normal. On the basis of tumor imprint cytology, the mass was diagnosed as a small round cell tumor, the differential diagnosis including malignant lymphoma, malignant melanoma and MS. The biopsy specimen showed proliferative small round cells with scant basophilic cytoplasm and nuclei containing occasional prominent nucleoli, suggesting the diagnosis of a lymphoproliferative disorder. Immunohistochemical examination revealed positive staining for myeloperoxidase, CD34, CD13, and CD117. Based on the findings, the patient was diagnosed as having myeloid sarcoma.
Conclusion : We report a case of vulval myeloid sarcoma diagnosed by tumor imprint cytology and biopsy.
