2020 Volume 59 Issue 4 Pages 181-185
Background : Ovarian cancer, as also fallopian tube cancer and primary peritoneal cancer, is difficult to diagnose in its early stages. We report a case that presented with only abnormal endometrial cytology, without any abnormal imaging findings.
Case : A 54-year-old woman with abnormal endometrial cytology was referred to our hospital. We performed endometrial biopsy, MRI, PET-CT and hysteroscopy, but could not establish a diagnosis. As the positive endometrial cytology persisted on repeat testing, we suspected the possibility of uterine or ovarian cancer, and performed surgery. Laparotomy revealed papillary lesions on the surface of the ovaries bilaterally. Histopathology was consistent with the diagnosis of high-grade serous carcinoma.
Conclusion : Endometrial cytology could offer an opportunity for the detection of ovarian, fallopian tube and peritoneal cancer. Diagnostic surgery may need to be considered in cases with persistently positive endometrial cytology where imaging examinations fail to show abnormal findings.