2020 Volume 59 Issue 6 Pages 286-290
Background : Primary squamous cell carcinoma of the endometrium is rare. Herein, we report a case of primary endometrial squamous cell carcinoma, with a review of the literature.
Case : The patient, a postmenopausal woman in her 50 s, presented with a history of menstrual disturbance. The findings of uterine cervical cytology were classified as ASC-H. Endometrial biopsy showed atypical squamous cells, either scattered or in a papillary pattern. Therefore, we diagnosed the lesion as squamous metaplasia with severe dysplasia. Laparoscopic hysterectomy with bilateral salpingo-oophorectomy was performed to make a definitive diagnosis. The final histopathological diagnosis was squamous cell carcinoma of the endometrium. We reviewed the cervical cytology findings and considered that the following could have been considered as possible indicators of squamous cell carcinoma : 1) atypical squamous cells ; 2) abnormal keratinizing cells ; 3) anuclear keratinizing cells ; 4) spindle-shaped cells.
Conclusion : Detection of the four aforementioned findings in the uterine cytology of a patient without apparent uterine cervical lesions should suggest the possibility of primary squamous cell carcinoma of the endometrium.
