A case of Rosai-Dorfman disease with many emperipolesis experienced by liquid-based cytology

Abstract

Rosai-Dorfman disease is a rare benign disease characterized by proliferation of histiocytes in the lymph nodes. We report a case of Rosai-Dorfman disease in a 60-year-old man who presented with multiple cervical and axillary lymphadenopathy and an abdominal mass. Liquid-based cytology of aspirated material revealed many large histiocytes with emperipolesis. The diagnosis of Rosai-Dorfman disease was established on the basis of the cytological and histopathological features.