2021 Volume 60 Issue 1 Pages 28-32
Background : Cytological differentiation between a hydatidiform mole and choriocarcinoma is challenging. Herein, we describe a case of histopathological diagnosis of a complete hydatidiform mole after hysterectomy.
Case : A 53-year-old woman (G5P3) presented to us with a history of irregular genital bleeding. Uterine cancer was suspected from the markedly elevated serum hCG levels and CT findings. Endometrial cytology revealed villi and mildly atypical intermediate trophoblasts, suggestive of hydatidiform mole. Histopathological diagnosis of the resected uterus confirmed it as complete hydatidiform mole with exaggerated placental site.
Conclusion : Endometrial cytology could be useful for the diagnosis of molar diseases and also for differentiating hydatidiform mole from choriocarcinoma.
