2022 Volume 61 Issue 2 Pages 122-128
Background : Combined small cell carcinoma is the generic term used to refer to small cell carcinoma occurring concomitantly with NSCLC, and small cell carcinoma occurring concomitantly with carcinosarcoma is rare. Herein, we report a case of combined small cell carcinoma of the lung with carcinosarcoma.
Case : The patient, in his 50 s, presented with bloody sputum and cough, and imaging chest computed tomography (CT) a 10 cm-sized tumor in the right upper lobe. Biopsy suggested the diagnosis of sarcomatoid carcinoma, and lobectomy was performed. Histopathology of the resected tumor revealed the diagnosis of combined small cell carcinoma with carcinosarcoma. Imprint cytology revealed adenocarcinoma cells, spindle-shaped mesenchymal cells, and a small number of small cell carcinoma cells.
Conclusion : It is difficult to make a diagnosis of combined small cell carcinoma by cytology alone. It is necessary to accumulate cytological data from these rare cases to enable cytological diagnosis.
