2025 Volume 64 Issue 1 Pages 7-11
Background : Renal collecting duct carcinoma is also called carcinoma of the Bellini duct. It is extremely rare among renal tumors and carries a very poor prognosis. Therefore, accurate diagnosis and early treatment are important. Herein, we report a case of renal collecting duct carcinoma, diagnosed by rapid intraoperative stamp cytology.
Case : A woman in her 70s visited our hospital complaining of abdominal pain. Abdominal CT revealed multiple enlarged lymph nodes extending from around the abdominal aorta to the bilateral iliac arteries, suggesting the possibility of malignant lymphoma. Other findings included low-density areas in the liver and right kidney. As malignant lymphoma was suspected clinically, intra-abdominal lymph node resection was performed. On the basis of rapid intraoperative stamp cytology, the tumor was diagnosed as an adenocarcinoma, as it showed malignant cells in a tubular or acinar arrangement, nucleus size anisotropy, and extensive nuclear fission. The diagnosis was confirmed by histopathology. Subsequent renal biopsy with immunohistochemical analysis led to the final diagnosis of renal collecting duct carcinoma.
Conclusion : In this patient, we were able to demonstrate the cytological characteristics of renal collecting duct carcinoma using stamp cytology material from a metastatic lymph node.