Abstract
In this paper, we discuss the possibility of cytological judgment of radiosensitivity of uterine cervical cancer by comparison between pre and postirradiation smears given 1, 000 rads by telecobalt external test irradiation.
The estimation of radiation effects on nuclei and the cytological presumption of histological typing in preirradiation smears have brought about satisfactory results;agreement between histological and cytological judgments of radiosensitivity was about 96.8%.
Cytological criteria of good sensitivity are as follows;
1) Disparity in size of chromatin particles and irregular distribution.
2) Irregularity of nuclear membrane with nuclear wrinkling with diminution of thickness of nuclear membrane.
3) Mature squamous cell carcinoma without pearlformation.
Those of poor sensitivity are as follows;
4) Existence of many unchanged viable cells and less disturbances of chromatines.
5) Existence of cells exibiting adenocarcinoma and carcinoma of intermediate type.
6) Clusters of cyanophilic cells having lacy, indistinct cell borders.