Abstract
There are a few reports on atypical cells appearing in the cytology specimens after D & C of pregnant women. Sequential cytopathological observations were made on 212 pregnant women receiving D & C at 2-3 months of pregnancy. Specimens were obtained with the endometrial aspiration instrument developed by the Cancer Institute Hospital, Tokyo. The sequential examinations were made on the 1st, 4th, 7th, 10th and 14th days after D & C. In addition to these smear specimens, histopathological as well as hormonal cytology examination was simultaneously made. Atypical cells, both single isolated and in clusters, as well as of syncytial type, were frequently detected. Their origin appears to be trophoblasts as well as the regenerative endometrial surface and glandular epithelium. Such kinds of atypical cells are sometimes deceivable as malignant neoplastic cells for their features, unless clinical information is noticed. We examined the nuclear DNA content of the atypical cells by microspectrophotometry. Some atypical cells were occasionally ploidy-like as malignant mode. These findings appear to be problematic.
