1982 Volume 21 Issue 1 Pages 72-75
A 62-year old woman was admitted to Miyagiken Seijinbyo Center for examination of a mass lesion in her left breast. The lesion was proved positive for malignancy and was diagnosed as scirrhous carcinoma by aspiration cytology. The patient underwent simple mastectomy.
The tumor, measuring 30×25 mm, was diagnosed histopathologically as infiltrating lobular carcinoma. Smear preparations of the resected material, treated with Papanicolaou staining, revealed following cytolo gical characteristics. Abundant cancer cells were scattered solitarily or arranged in small clusters comprising less than ten cancer cells. Indian filings were noticed. There were 29 pairs of cells (pair cells) out of 300 cells. Most cancer cells were small. The long and short axes of nuclei distributed in the range of 6-11μm (mean 8.83μm, S. D. 1.07μm) and of 5-10μm (mean 7μm, S. D. 1.02μm) respectively. Shape of nuclei was basically circular, but nuclear indentation was recognized in 29 out of 300 nuclei. Nuclear chromatins generally showed finely reticular or finely granular pattern, but coarsely granular chromatins were partly seen. Most of the cancer cells presented only one nucleolus of 1μm in size.
