Abstract
Study on detection of malignant cells in the routine wet-mount urine sediment was reported. In our laboratory, during 1973 and 1979, 68 malignant caces of the urinary system were diagnosed in 389, 760 urine samples by routine examination. The lesions detected include 5 cases of urinary bladder carcinoma, 1 renal pelvic carcinoma, 4 with urinary bladder invasion from uterine cervical carcinoma, 1 from prostate carcinoma, 1 from rectal carcinoma, etc. When atypical cells were found in the wet-mount specimens under the conventionalbright optical microscopic fields, the cover-glass was removed and subsequent PAP or Giemsa staining was employed for detailed cytological observation. Supravital staining using. URI-Cel appeared to be appreciable procedure. Variety of cell size, tendency to form cell clusters, irregular and stiff nuclear rim, coarse chromatinic structure, etc. were the significant features of malignant cells in the wet-mount specimens.